1, 2021, when the Omicron variant was circulating, about 10 percent experienced long-term symptoms or long COVID after six months. “We are incredibly grateful to our study participants, many of whom continue to suffer with few answers, for helping us take this first step toward understanding this condition.”īased on a subset of 2,231 patients in this analysis who had a first COVID-19 infection on or after Dec. Emery, co-Investigator for the MaineHealth RECOVER site. “We see through this study that long COVID can take many forms and impacts all parts of the body,” said Dr. They also found that certain symptoms occurred together, and defined four subgroups or “clusters” with a range of impacts on health. With these scores in hand, researchers identified a meaningful threshold for identifying participants with long COVID. By assigning points to each of the 12 symptoms, the team gave each patient a score based on symptom combinations. They then established a scoring system based on patient-reported symptoms. They assessed more than 30 symptoms across multiple body areas and organs and applied statistical analyses that identified 12 symptoms that most set apart those with and without long COVID: post-exertional malaise, fatigue, brain fog, dizziness, gastrointestinal symptoms, heart palpitations, issues with sexual desire or capacity, loss of smell or taste, thirst, chronic cough, chest pain and abnormal movements. Of the study participants, 8,646 had COVID-19 and 1,118 did not. Researchers examined data from 9,764 adults, including 119 people who participated through MHIR. “RECOVER, as part of a broader government response, in collaboration with academia, industry, public health institutions, advocacy organizations and patients, is making great strides toward improving our understanding of long COVID and its associated conditions.” Levine, MD, Assistant Secretary for Health for the U.S. “Americans living with long COVID want to understand what is happening with their bodies,” said Adm. Clinical symptoms can vary and include fatigue, brain fog and dizziness, and last for months or years after a person has had COVID-19. The goal is to eventually find potential treatments for long COVID. These findings come from the NIH’s Researching COVID to Enhance Recovery (RECOVER) initiative, a nationwide effort dedicated to understanding why some people develop long-term symptoms following COVID-19, and most importantly, how to detect, treat and prevent long COVID. It was co-authored by Ivette Emery, PhD, a translation scientist at the MaineHealth Institute for Research (MHIR). The study is funded by the National Institutes of Health (NIH), and has been published in JAMA, the Journal of the American Medical Association. PORTLAND, Maine – Initial findings from a study of nearly 10,000 Americans, including those in Maine, indicate that certain symptoms of long COVID occur together and that long COVID was more common and severe in study participants infected before the 2021 Omicron variant.
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